|
KMID : 1102020190490010014
|
|
Applied Microscopy
2019 Volume.49 No. 1 p.14 ~ p.14
|
|
|
Next-generation fluorescent nucleic acids probes for microscopic analysis of intracellular nucleic acids
|
|
Okamoto Akimitsu
|
|
|
Abstract
|
|
|
|
Fluorescence imaging of nucleic acids is a very important technique necessary to understand gene expression and the resulting changes in cell function. This mini-review focuses on sequence-specific fluorescence imaging of intracellular RNA and methylated DNA using fluorescent nucleic acid probes. A couple of functional fluorescent nucleic acid probes developed by our laboratory are introduced and the examples of their application to fluorescence imaging of intracellular nucleic acids are described.
|
|
|
KEYWORD
|
|
|
Methylated DNA, RNA, Fluorescence, Single cell imaging, Synthetic nucleic acid
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|